Libotlolo tsa khalase tsa React ke libotlolo tsa khalase tse sebelisetsoang ho boloka li-reagents tsa lik'hemik'hale. Hangata libotlolo tsena li entsoe ka khalase e thibelang asiti le alkali, e khonang ho boloka lik'hemik'hale tse fapaneng tse kang li-acids, bases, solutions le solvents ka mokhoa o sireletsehileng.